How to use SeekSoul Online cloud platform the best one-stop single-cell multi-omics data mining and visualization online tool

SeekSoul covers a full set of processes including:

single-cell transcriptome
single-cell immunome
SeekSoul's self-developed single-cell spatial transcriptome product standard analysis and advanced analysis.

The analysis results are highly consistent with the code execution analysis results, providing users with comprehensive and in-depth data analysis solutions in multiple fields including disease mechanism exploration, biological target mining, and basic scientific research.

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Flanders Research project based on SeekSpace technology has been approved

Cancer Letters | Zhongshan Hospital of Fudan University and Ruijin Hospital of Jiaotong University reveal pan-cancer immune features mediated by major histocompatibility complex

Zheng Ke/Lin Mingyan/Guo Xuejiang/Tan Yueqiu's collaborative team systematically identified RNA-binding proteins in mammalian spermatogenic cells

Neuro-oncology | Project article: Toll-like receptor (TLR) agonists promote tertiary lymphoid structure (TLS) formation and improve anti-glioma immunity

Xunyin Biotechnology Co., Ltd. for winning the national-level specialized and innovative

SUPPORTED DATA TYPES

RDS
Matrix
H5
H5D
Loom

Success Stories

2024.06.10-Cancer Cell-Tumor cells impair the formation of immune synapses through metabolites enriched in the central nervous system

2024.03.29-Science Advances-Single-cell atlas of the inner column of the ascidian reveals the evolutionary origin of the vertebrate pharyngeal organ

2024.03.07-J Immunother Cancer-Web-based screening identifies sitagliptin as an anti-tumor drug targeting dendritic cells

2024.05.13-Nature Nanotechnology-Janus lipase repairs damaged tissue and promotes healing

2024.07.23-Cell Reports-Single-cell and spatial transcriptome techniques reveal the spatial organization and dynamic changes of silk gland cells in silkworms

2024.07.10-Nature-Tumor vascular atlas at single-cell resolution

2024.07.20-Journal of Translational Medicine-Single-cell genomic studies of computational cell states to distinguish aberrant hematopoiesis and activated microenvironment in myelodysplastic syndrome (MDS)

2024.06-Cancer Letters-Unveiling a pan-cancer immune signature mediated by major histocompatibility complex by integrating single-cell and bulk RNA sequencing

2024.06.14-Clinical Kidney Journal-Comprehensive analysis of untreated primary membranous nephropathy at the single-cell transcriptome level

2024.01.20-Nature Communications-Macro CD5L+ affects gemcitabine-oxaliplatin-lenvatinib-anti-PD1 combination therapy in intrahepatic cholangiocarcinoma by aggravating CD8+ T cell exhaustion

2024.03.15-International Journal of Molecular Sciences-6-Methoxybenzofuran compound I-9 based on the BMP2-ERK-ATF4 axis can be used as a candidate drug for promoting bone formation and preventing osteoporosis

2024.07.22-Gene-Using the fragmentation characteristics of maternal plasma free DNA to non-invasively determine gene expression in placental tissue

2024.08.29-science-Map of RNA-binding proteins during mammalian spermatogenesis

2024.08.27-Neuro-Oncology-TLR agonists promote the formation of tertiary lymphoid structures and improve anti-glioma immunity

2024.07.02-Biology Direct-Single-cell transcriptome analysis reveals insights into ovarian fibrosis in obese mice

2024.08.01-Hepatobiliary Surgery and Nutrition-Immunosuppression and phenotypic plasticity in the human hepatobiliary carcinoma landscape

2024.03.25-Journal of Translational Medicine-Single-cell RNA sequencing reveals that Lewis lung cancer-bearing mice recruit M2-like CCL8-high-expressing macrophages after hypofractionated radiotherapy

2024.05.10-International Immunopharmacology-CXCR6 defines a therapeutic subtype of the CD4 cytotoxic T cell lineage for adoptive cell transfer therapy of pediatric B-cell acute lymphoblastic leukemia

2023.7.20-Annals of the Rheumatic Diseases-Single-cell transcriptome analysis describes cellular and molecular alterations in the submandibular gland and blood in IgG4-related diseases

2022.3.14-Front Bioeng Biotechnol-Mesenchymal stem cell culture method based on small molecule cocktail strategy

2022.12.15-Fertility and Sterility-scRNA-seq Decidual tissue microenvironment in women with miscarriage

2023.1.20-Journal of Medicinal Chemistry-Efficacy, mechanism and structure-activity relationship of 6-methoxybenzofuran derivatives as useful tools for the treatment of senile osteoporosis

2023.1.9-Frontiers in Genetics-Single-cell RNA sequencing reveals potential mechanisms of intratumor heterogeneity and perineural invasion in malignant progression of prostate cancer

2023.3.17-Nature Communications-Dectin-1 inhibitors prevent colorectal tumorigenesis by inhibiting prostaglandin E2 production and enhancing IL-22 binding protein expression in myeloid-derived suppressor cells

2023.3.23-Cancer Cell-Neutralization of IL-8 enhances the efficacy of immunotherapy for glioma

2023.4.25-Blood Cancer Journal-Allogeneic and autologous anti-CD7 CAR-T cells for the treatment of relapsed/refractory (R/R) T-cell malignant lymphoma

2023.4.29-Leukemia-Glucose distribution in the bone marrow microenvironment of patients with acute myeloid leukemia

2022.1.10-Nature Communications-Dynamic transcriptome and chromatin structure of granulosa cells during chicken folliculogenesis

2023.8-HemaSphere-Single Cell Atlas of HIV-Associated Diffuse Large B-Cell Lymphoma

2023.9-Science Bulletin-Single-cell dynamics of postnatal pig liver development

2023.9-Cell Discovery-Self-recruitment of innate immune response, overactivation of neutrophils and changes in cardiomyocyte phenotype in fulminant viral myocarditis

2023.10- BMC Medical Genomics-Using single-cell transcriptome to explore the global immune landscape of peripheral blood mononuclear cells in patients with H5N6 infection

2023.12.21-Nature aging-NADase CD38 elevation is a key determinant of early ovarian aging

20024.01.12-Journal of Cellular Physiology-Single-cell transcriptome analysis reveals tumor microenvironment heterogeneity and hypervascularization in human carotid body tumors

2024.01.18-Zoological Research-Single-cell analysis of porcine cecum at different developmental stages